Police officers stand guard near the attacked Christmas market in Berlin, capital of Germany, on December 21, 2016.
It was believed that the man, who hired a rental vehicle to carry out the attack, was also in possession of a knife at the time.
He was seriously injured following the brief stand-off and rushed to hospital.
Police said that at the moment they are unclear about the man's motives but added they don't suspect the attack to be terrorism-related.
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The incident occurred around 4pm local time, a police spokesman has told Der Spiegel.
Police spokeswoman Anne Baas said one of the three people hit outside a bakery was also seriously injured.
"At the current stage of the investigation there is nothing to suggest that it was a terrorist" act, the police said.
German authorities are on high-alert after a man drove a truck into Christmas crowds at a Berlin market, killing 12 people.
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